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US cuts $500M in mRNA vaccine funding, raising concerns over pandemic readiness

Robert F. Kennedy Jr. speaks during a hearing with the House Judiciary Subcommittee on the Weaponization of the Federal Government on Capitol Hill on July 20, 2023, Washington, DC., United States. (AFP Photo)
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Robert F. Kennedy Jr. speaks during a hearing with the House Judiciary Subcommittee on the Weaponization of the Federal Government on Capitol Hill on July 20, 2023, Washington, DC., United States. (AFP Photo)
By Newsroom
August 08, 2025 11:10 AM GMT+03:00

The U.S. Department of Health and Human Services (HHS) will end nearly $500 million in funding for 22 mRNA vaccine projects, a decision that public health experts say could leave the country unprepared for future pandemics.

What’s happening:

  • Health Secretary Robert F. Kennedy Jr., a longtime vaccine skeptic, announced on Tuesday that the U.S. will cut nearly $500 million in funding for mRNA vaccine projects.
  • The move affects 22 projects, including vaccines for bird flu, seasonal flu, RSV, cytomegalovirus, Zika, Epstein-Barr virus, and hepatitis B.
  • Contracts with major companies such as Moderna and Pfizer are among those being terminated.

Kennedy’s reasoning:

  • Said his team had “reviewed the science, listened to the experts, and acted.”
  • Claimed “mRNA technology poses more risk than benefits against these respiratory viruses” and that the shots “fail to protect effectively against upper respiratory infections like COVID and flu.”
  • Plans to shift funding to “safer, broader vaccine platforms” such as whole-virus vaccines.

Expert reaction:

  • Jeff Coller, Bloomberg distinguished professor of RNA biology at Johns Hopkins University, told Live Science the cancellation was “a shot across the bow to the entire industry” and will make companies “question, should we continue to invest in these programs within the United States?”
  • Warned: “Not continuing to investigate the usage of a technology that has proven itself is completely reckless and puts America and Americans in harm’s way.”
  • Noted that clinical trials for influenza, RSV, cytomegalovirus, Zika, Epstein-Barr virus, and hepatitis B are already affected.
  • Said mRNA has applications beyond infectious disease, including cancer therapies, gene-editing treatments, and autoimmune disorders: “By undermining mRNA-based work, we’re potentially limiting the ability to do this true personalized medicine approach of gene editing that could save millions of people’s lives every year.”

Experts warn against weakening US preparedness, global leadership

Scientists strongly reject Health Secretary Robert F. Kennedy Jr.'s claims. “His science is backwards, as it often is,” Dr. Peter Hotez, dean of Baylor College of Medicine’s National School of Tropical Medicine, told NPR.

“This is a proven technology for emerging respiratory viruses. It is extremely safe and has been incredibly effective.”

Michael Head, a global health researcher at the University of Southampton, told The Guardian, “The mRNA vaccines saved about 20 million lives globally in the first year of their roll-out.” He described the platform as “plug-and-play” because it can be updated quickly to address new variants, reducing the threat from infectious diseases.

Michael Osterholm, who runs the Center for Infectious Disease Research and Policy at the University of Minnesota, called the cuts “the most dangerous public health judgment that I’ve seen in my 50 years in this business.” Jennifer Nuzzo, who leads the Pandemic Center at Brown University, told NPR the decision “absolutely leaves the country vulnerable.”

Coller noted that the speed of mRNA vaccine development was critical during COVID-19. “We were able to identify a pathogen, have a sequence, make a possible vaccine, develop that in nine months, and deploy it in the next three months. That’s unparalleled in human history,” he said. Traditional vaccines can take three to five years to develop, he added.

Impacts could extend to cancer research, US national security

Experts say the cuts could slow cancer research and gene therapy development. Coller said researchers working on mRNA-based cancer therapies are “scared to even mention that they have mRNA-based medicines, because their patients will suffer if the funding gets cut off.”

Former US biodefense official Chris Meekins said the decision could “put the US at a strategic national security disadvantage.” Rick Bright, who once led BARDA, said, “We’re taking our country from 2025 back to 1940, and we all know that’s a recipe for disaster and failure.”

Coller warned that the funding withdrawal could cause a “brain drain” as scientists and companies move operations abroad. He said other countries, including China, are increasing investment in mRNA research. “If a pandemic comes out, we’re going to be caught asking China for their vaccines,” he said.

Hotez cautioned that undermining mRNA research sends the wrong message to the public. “They’re trying to make the case to the public that mRNA technology doesn’t work very well and it’s unsafe. And that’s absolutely untrue,” he said.

The decision marks a significant policy shift for the US health department, with potential consequences for medical research, pandemic readiness, and the country’s role in global vaccine development.

August 08, 2025 11:50 AM GMT+03:00
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