Zach Cregger's "Resident Evil" opened with $108.3 million at the global box office, powered by a franchise-record $60 million debut in the United States and Canada, according to studio estimates released Sunday.
The Sony Pictures horror film brought in $60 million from 3,684 theaters across North America, giving the video game-inspired franchise its biggest opening since the film series began in 2002.
The result also marked the strongest opening of Cregger's career, following his work on Weapons and Barbarian.
With $60 million from its opening weekend alone, the new Resident Evil has already surpassed the entire North American theatrical runs of every previous film in the franchise except 2010's Resident Evil: Afterlife, which finished with $60.1 million.
International markets added another $48.3 million, pushing the film's worldwide opening to $108.3 million. The production reportedly cost $75 million, excluding marketing expenses.
The film stars Austin Abrams as Bryan, a medical courier who is forced to fight for survival after entering Raccoon City.
The movie has also drawn strong reviews, reaching a 95% critics' score on Rotten Tomatoes as of Monday.
Based on Capcom's survival-horror video game series, the new release is the eighth live-action "Resident Evil" film and the first installment since 2021's "Resident Evil: Welcome to Raccoon City."